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Lacking FDA approval and recent extensive peer-reviewed data, its use for anti-aging, bodybuilding, or other non-FDA approved purposes is not evidence-based and carries substantial risks, including reported hypersensitivity reactions and unknown long-term endocrine disruption [fda.gov], [mayoclinic.org]
10.1161/CIRCULATIONAHA.111.041418 [DOI] [PMC free article] [PubMed] [Google Scholar] 181.Bhatt DL, Cavender MA
Finally, some commonly used drugs (e.g., glucocorticoids and GLP-1RAs) can also affect intra-portal insulin levels that modulate the GH/IGF-I axis either by increasing or decreasing hepatic GH sensitivity, as reflected by the discordant GH and IGF-I levels
Its mechanism of action entails the emulation of the hormone GLP-1, naturally produced in the gut as a response to food intake, making you feel fuller
however, these effects are not universal and may differ from person to person
