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Beneficial effects of leptin on obesity, T cell hyporesponsiveness, and neuroendocrine/metabolic dysfunction of human congenital leptin deficiency

The authors stated that the peptide had the effect of increasing melatonin concentration in the test subjects, thus contributing to enhanced control of the sleepwake cycle [6]

In my clinical experience, one test is consistently missing from this picture: serum vitamin B12

PMID: 178 UntererMKhan MirzaeiMDengL

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Prophylactic immunization of the alternatively spliced extra domain (ED)-B of fibronectin efficiently reduced growth of syngeneic subcutaneous tumors [320], and therapeutic vaccination against ED-A after tumor development reduced metastatic dissemination in the MMTV-PyMT model of metastatic mammary carcinoma [321]