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Epidermal fatty acid binding protein promotes skin inflammation induced by high-fat diet

Chen L, Zhao R, Kang Z, Cao Z, Liu N, Shen J, et al

10.1186/s12974-022-02511-0 31 DingZ.YangC.ZhaiX.XiaY.LiuJ.YuM

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Additionally, a chromosome aberration assay using human peripheral blood lymphocytes exposed to the extract at concentrations of 0.25, 0.5, 1, and 2 mg/ml and in vivo micronucleus test in mammalian erythrocyte cells that received doses of 500, 1,000, and 2,000 mg/kg also showed that the extract had no inhibitory effects on the mitotic index, the formation of micronuclei, or cell proliferation, and did not induce chromosomal abnormalities

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