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What you should not do is run it 7 days/week indefinitely the receptor desensitization issue still applies

doi: 10.1053/j.nainr.2016.09.019

Experimental studies report activation of signaling mechanisms related to vascular remodeling, including Notch-associated pathways and endothelial cell activation in angiogenesis models [8]

Chrononutrition is an important modulator of peripheral clocks in the circadian system controlling blood pressure rhythms (46), partly through the hypothalamuspituitaryadrenal (HPA) axis