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Less common presentations of gout are associated with overproduction of uric acid, which can be caused by increased activity of PRPP synthetase or deficiency in purine recycling enzyme HGPRT caused by Lesch-Nyhan syndrome (figure 7.10)

Collectively, carnitine and its acyl derivatives hold promise as dual-purpose biomarkers in DKD, serving as prognostic indicators of disease progression and as molecular tools for monitoring therapeutic response

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doi: 10.1371/journal.pone.0170900

Supplementation of L-carnitine in athletes: Does it make sense