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The bioavailability through the nasal mucosa has been shown to be comparable to, and in some aspects superior to, injection methods for this particular peptide

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For live cell imaging, Calu-3, Huh7.5, and A549 cells were treated with phenformin in concentrations of 12800 M to 0.2 M and atpenin A5 in concentrations of 640 M to 0.15 M in two-fold dilution