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Each week, the dose will go up until it reaches a maximum of 15 mg

The table gives Contrave an onset of 4 to 8 weeks with minimal nausea but possible stimulant side effects, against 2 to 4 weeks for GLP-1 agonists with common early nausea and vomiting that improves over time

It has a 94% structural similarity to glucagon-like peptide (GLP)-1 and binds the GLP-1 receptor with an affinity of 0.38 nM

The prepaid bundles make costs predictable, and for patients who want to avoid insurance battles, this can feel refreshingly straightforward

But maximum weight loss is not always the deciding factor