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Translating Preclinical Data to Human Potential The NHP-to-human pharmacokinetic scaling suggests ASC35 may achieve a 30-day half-life or longer in humans

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These complementary mechanisms conferred dual enhancement of drug transport: paracellular passage via modulated tight junctions and transcellular uptake through endocytic pathways

El GLP-1 estimula la secrecin de insulina de manera dependiente de glucosa , es decir, acta principalmente cuando los niveles estn elevados tras la ingesta, y al mismo tiempo inhibe la liberacin de glucagn