Liraglutide causes nausea and rare cases of pancreatitis but demonstrates safety and effectiveness for most individuals, supporting its role in managing obesity and reducing related risks (35)
Green JB, Mottl AK, Bakris G, Heerspink HJL, Mann JFE, McGill JB, Nangaku M, Rossing P, Scott C, Gay A, et al
This effect has led to companies creating GLP-1 medication specifically for weight management, including the FDA-approved drugs Wegovy and Zepbound
Dapagliflozin reduced the primary composite outcome (sustained 50% eGFR decline, ESKD, or death from renal or cardiovascular causes) by 39% compared to placebo [47]
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However, patients ages, medical histories and duration of Ozempic use can vary greatly, and require individualized approaches