D.RoveriA.SchomburgD.et al
While they can offer antioxidant support and brighten surface-level pigmentation, their effects are limited compared to oral or injectable forms, as glutathione molecules struggle to penetrate deeply into skin layers
2B& 2C)
Pebp1 wardens ferroptosis by enabling lipoxygenase generation of lipid death signals
Deficiency in vitamin B complex can lead to nerve damage or dysfunction, resulting in sensations like numbness, tingling, or a "pins and needles" feeling in the hands and feet
Thanks to their expanded interface with the target protein, peptide PROTACs demonstrate superior potency, higher selectivity, and reduced toxicity compared to low molecular weight compounds, especially when targeting proteins lacking well-defined binding pockets (Kargbo, 2019)