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American Journal of Health-System Pharmacy, 60(12), 1237-1241

Do not discontinue prescribed B12 treatment without medical advice, as this may be managing an important deficiency state

Biotin injections are generally well-tolerated, but some people may experience mild side effects, such as temporary redness or soreness at the injection site

November 11, 2022 Is nutritional yeast a good source of B-12 and other B vitamins

These limitations do not invalidate preclinical findings but emphasize the need for human clinical trials with appropriate sample sizes, standardized protocols, and validated outcome measures before establishing clinical efficacy in human patients