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Pyruvate is metabolized to lactate in the cytosol or converted to acetyl coenzyme A (acetyl-CoA) in the mitochondria to fuel the tricarboxylic acid (TCA) cycle, enhance OXPHOS, and generate ATP [18,19]

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Mol Metab 2020;32:160167 [DOI] [PMC free article] [PubMed] [Google Scholar] 92

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