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Telomeres, telomerase, and aging: origin of the theory

However, if the purpose of the drug is to be taken up by the liver, then first-pass metabolism may be irrelevant (the drug is still metabolized into hepatic glutathione, which is what matters)

Mischley LK, Allen J, Bradley R (2012) Coenzyme Q10 deficiency in patients with Parkinsons disease

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Because these symptoms overlap with so many other things, they're easy to miss, which is part of why the post recommends regular medical check-ups to catch deficiencies early