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Evaluating the Efficacy of Triple Hormone Receptor Agonists: A Comparative Study on Retatrutide in Obesity Models

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The effect of -caryophyllene oxide (CRYO), -caryophyllene, -humulene, nerolidol and valencene on ABC-mediated efflux of pre-loaded fluorescent substrates (rhodamine for MDR1, calcein for MRP1 and MRP2, fluorescein for MRP3, MRP4 and MRP5 and mitoxantrone for BCRP) was determined by flow cytometry after 30 min

16 weeks 6 vials Through 6 mg phase = 52 mg total