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However, heterogeneity was considerably reduced vs placebo in a sensitivity analysis excluding one trial with short duration and one trial in which all participants were on background insulin therapy

[DOI] [PubMed] [Google Scholar] Rigault C., Mazu F., Bernard A., Demarquoy J., Le Borgne F

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Unlike traditional hormones, MOTS-c acts as a mitochondrial signal, translocating to the nucleus to regulate gene expression in response to metabolic stress

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doi: 10.1021/ja01543a060 39 HardelandR