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GLPs demonstrates defensive impacts against diabetes and its associated complications including nephropathy, hepatopathy, cardiomyopathy, refractory wound healing, neuropathy, retinopathy, and erectile dysfunction--through mechanisms involving oxidative stress modulation, glucolipid metabolism regulation, anti-apoptosis, islet cells repair, and the gut microbiota remodeling

At 48 weeks, a weight reduction of 5%, 10%, and 15% had occurred in 100%, 93%, and 83% of those who received 12 mg of retatrutide and 27%, 9%, and 2% of those who received placebo

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