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In a hydrogen peroxide-induced oxidative stress model using porcine IECs, extracellular polysaccharides from LGG accelerated ROS clearance by upregulating antioxidant enzyme expression and downregulating oxidative stress-related proteins

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Beyond minoxidil, other topical actives have shown promise in combination: copper peptides (Kuceki 2025) demonstrated significant results in resistant cases, platelet-rich plasma (PRP) has been studied in network meta-analyses, and GHK-Cu serums work through complementary mechanisms