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Since, to our knowledge, this is the first case report that describes the effectiveness of dual therapy with a GLP1-RA and a SGLT2i in type A IR syndrome, further research is needed to assess the role of these glucose-lowering agents in the treatment of this condition

Lu Z, Badgwell DB, Le K, Suh GK, Das P, Andreeff M , Ahmed AA, Liao WS, Bast Jr RC

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Osmolytes except urea function in maintaining the native folded conformation of proteins by increasing the near free energy of unfolded state of the protein (Khan et al., 2010)

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Indeed, skeletal muscle metabolism of lipids has been shown to be impaired in type 2 diabetics