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Rare but serious risks can include: Significant cardiovascular symptoms Severe anxiety or agitation Psychosis (more likely with high doses/misuse) in rare cases If you stop suddenly after heavy use, you may experience withdrawal symptoms like fatigue, low mood, anxiety, and other symptoms

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doi:10.1016/j.biopha.2018.08.088 199

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Other Side Effects of Semaglutide Beyond eye health concerns, there are other risks and potential side effects to be aware of, especially if taking macro doses of semaglutide