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At room temperature, degradation can begin relatively quickly

This analysis was conducted with an extracellular flux analyzer (Agilent Technologies, Santa Clara, CA, USA) utilizing the Seahorse XF HS Mini platform

Ashoori, M., & Saedisomeolia, A

USA 104 , 52235228 (2007)

Here, they undergo incomplete, alternative oxidation pathways that generate massive amounts of free radicals and reactive oxygen species (ROS), further damaging the delicate mitochondrial membranes and the very enzymes required for energy production