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Research Findings The research history of AOD9604 spans multiple phases of preclinical and clinical development, with generally positive findings regarding efficacy for body fat reduction and favorable safety compared to growth hormone, though ultimate regulatory approval has remained elusive

The SURMOUNT-1 Phase 3 trial published in the New England Journal of Medicine demonstrated 20.9% mean body weight reduction at 72 weeks on tirzepatide 15mg weekly versus 3.1% with placebo