Yu J, Wang J, Zhang Y, Chen G, Mao W, Ye Y, Kahkoska AR, Buse JB, Langer R, Gu Z
The genetic layer these programs leave out Ozempic-focused programs does not account for the upstream genetic architecture that shapes how any GLP-1 compound behaves in a given body
4, constituting approximately 70% of its composition 21
Oligo Sequences Codon-optimized SLC25A39 sequence ATGGCAGACCAGGACCCCGCGGGCATCTCACCTCTCCAGCAGATGGTCGCATCTGGAACAGGGG CAGTCGTCACAAGTTTGTTCATGACCCCACTTGATGTAGTGAAAGTCCGGCTTCAATCACAACGCC CTAGCATGGCCAGCGAGCTGATGCCGAGCTCCAGGCTCTGGTCACTTTCTTATACGAAGCTTCCC TCTTCTCTCCAGTCTACGGGTAAATGTTTGCTTTATTGTAACGGCGTACTCGAACCTCTGTATTTGT GTCCAAATGGAGCACGCTGCGCCACGTGGTTTCAGGACCCAACTCGATTTACCGGCACAATGGAC GCATTTGTCAAGATAGTAAGACACGAGGGTACAAGAACGCTTTGGAGCGGCCTCCCTGCTACGTT GGTGATGACGGTTCCCGCAACGGCCATATACTTTACAGCCTACGACCAGCTGAAGGCCTTTCTGT GTGGTAGGGCACTTACCTCAGACCTTTACGCTCCAATGGTCGCAGGGGCCCTTGCAAGACTTGGT ACGGTCACTGTAATAAGTCCGCTCGAACTCATGAGGACAAAACTCCAAGCTCAGCACGTGAGCTA CCGGGAACTGGGGGCTTGTGTACGCACAGCGGTCGCGCAAGGCGGCTGGAGGAGTCTGTGGCT GGGTTGGGGGCCCACGGCCCTCCGGGACGTACCGTTTTCTGCGCTTTATTGGTTTAACTACGAGC TTGTGAAATCTTGGCTCAATGGATTCCGGCCGAAAGACCAGACCTCCGTTGGAATGTCTTTCGTCG CCGGGGGCATTTCCGGCACGGTGGCCGCCGTGCTGACCTTGCCATTCGACGTTGTTAAGACCCA GCGACAGGTCGCTTTGGGGGCAATGGAGGCCGTGCGGGTGAACCCACTCCACGTTGACAGTACA TGGTTGCTGCTCCGCCGCATCCGGGCCGAAAGCGGAACTAAAGGTCTGTTTGCTGGATTTCTTCC GCGAATCATTAAGGCTGCGCCATCTTGTGCAATCATGATCTCTACATACGAGTTTGGAAAATCCTT CTTTCAGAGGCTTAATCAGGACAGACTGCTCGGAGGGTAA SLC25A39 D226A ATGGCAGACCAGGACCCCGCGGGCATCTCACCTCTCCAGCAGATGGTCGCATCTGGAACAGGGG CAGTCGTCACAAGTTTGTTCATGACCCCACTTGATGTAGTGAAAGTCCGGCTTCAATCACAACGCC CTAGCATGGCCAGCGAGCTGATGCCGAGCTCCAGGCTCTGGTCACTTTCTTATACGAAGCTTCCC TCTTCTCTCCAGTCTACGGGTAAATGTTTGCTTTATTGTAACGGCGTACTCGAACCTCTGTATTTGT GTCCAAATGGAGCACGCTGCGCCACGTGGTTTCAGGACCCAACTCGATTTACCGGCACAATGGAC GCATTTGTCAAGATAGTAAGACACGAGGGTACAAGAACGCTTTGGAGCGGCCTCCCTGCTACGTT GGTGATGACGGTTCCCGCAACGGCCATATACTTTACAGCCTACGACCAGCTGAAGGCCTTTCTGT GTGGTAGGGCACTTACCTCAGACCTTTACGCTCCAATGGTCGCAGGGGCCCTTGCAAGACTTGGT ACGGTCACTGTAATAAGTCCGCTCGAACTCATGAGGACAAAACTCCAAGCTCAGCACGTGAGCTA CCGGGAACTGGGGGCTTGTGTACGCACAGCGGTCGCGCAAGGCGGCTGGAGGAGTCTGTGGCT GGGTTGGGGGCCCACGGCCCTCCGGGCAGTACCGTTTTCTGCGCTTTATTGGTTTAACTACGAGC TTGTGAAATCTTGGCTCAATGGATTCCGGCCGAAAGACCAGACCTCCGTTGGAATGTCTTTCGTCG CCGGGGGCATTTCCGGCACGGTGGCCGCCGTGCTGACCTTGCCATTCGACGTTGTTAAGACCCA GCGACAGGTCGCTTTGGGGGCAATGGAGGCCGTGCGGGTGAACCCACTCCACGTTGACAGTACA TGGTTGCTGCTCCGCCGCATCCGGGCCGAAAGCGGAACTAAAGGTCTGTTTGCTGGATTTCTTCC GCGAATCATTAAGGCTGCGCCATCTTGTGCAATCATGATCTCTACATACGAGTTTGGAAAATCCTT CTTTCAGAGGCTTAATCAGGACAGACTGCTCGGAGGGTAA SLC25A39 K329A gccaccATGGCAGACCAGGACCCCGCGGGCATCTCACCTCTCCAGCAGATGGTCGCATCTGGAACA GGGGCAGTCGTCACAAGTTTGTTCATGACCCCACTTGATGTAGTGAAAGTCCGGCTTCAATCACAA CGCCCTAGCATGGCCAGCGAGCTGATGCCGAGCTCCAGGCTCTGGTCACTTTCTTATACGAAGCT TCCCTCTTCTCTCCAGTCTACGGGTAAATGTTTGCTTTATTGTAACGGCGTACTCGAACCTCTGTAT TTGTGTCCAAATGGAGCACGCTGCGCCACGTGGTTTCAGGACCCAACTCGATTTACCGGCACAAT GGACGCATTTGTCAAGATAGTAAGACACGAGGGTACAAGAACGCTTTGGAGCGGCCTCCCTGCTA CGTTGGTGATGACGGTTCCCGCAACGGCCATATACTTTACAGCCTACGACCAGCTGAAGGCCTTT CTGTGTGGTAGGGCACTTACCTCAGACCTTTACGCTCCAATGGTCGCAGGGGCCCTTGCAAGACT TGGTACGGTCACTGTAATAAGTCCGCTCGAACTCATGAGGACAAAACTCCAAGCTCAGCACGTGA GCTACCGGGAACTGGGGGCTTGTGTACGCACAGCGGTCGCGCAAGGCGGCTGGAGGAGTCTGT GGCTGGGTTGGGGGCCCACGGCCCTCCGGGACGTACCGTTTTCTGCGCTTTATTGGTTTAACTAC GAGCTTGTGAAATCTTGGCTCAATGGATTCCGGCCGAAAGACCAGACCTCCGTTGGAATGTCTTTC GTCGCCGGGGGCATTTCCGGCACGGTGGCCGCCGTGCTGACCTTGCCATTCGACGTTGTTAAGA CCCAGCGACAGGTCGCTTTGGGGGCAATGGAGGCCGTGCGGGTGAACCCACTCCACGTTGACAG TACATGGTTGCTGCTCCGCCGCATCCGGGCCGAAAGCGGAACTAAAGGTCTGTTTGCTGGATTTC TTCCGCGAATCATTGCAGCTGCGCCATCTTGTGCAATCATGATCTCTACATACGAGTTTGGAAAAT CCTTCTTTCAGAGGCTTAATCAGGACAGACTGCTCGGAGGGTAA These gene fragments were purchased from Twist Biosciences, and directly cloned into linearized pMXS-IRES-Blast (Cell Biolabs, RTV-016)
We give you the tools and instructions to administer the medication at home (you can also come into the office for weekly injections)
At Set Point, we believe in personalized treatment plans, as we know that every patients journey is different
