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Instead, the glucagon component appears to increase basal metabolic rate by 10-15% and shift the body toward preferential fat oxidation while sparing muscle tissue

doi: 10.3390/stresses2010005

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Epigenetic modifications, such as increased methylation and expression of the pseudogene PTENP1, occur with age, possibly as a protective mechanism against malignancy [43]

Basic Clin Pharmacol Toxicol 2006