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Curr Opin Genet Dev 65:126137

52 The discrepancy of clinical efficacy of these two drugs is due at least partially to their difference of proportion of GLP-1 and GIP activity

GHK-Cu (Copper Tripeptide-1) Originally isolated from human plasma, GHK-Cu has become a cornerstone peptide in regenerative and tissue biology research

HPLC grade acetonitrile (ACN), acetic acid and water, and reagent grade trifluoroacetic acid (TFA) were purchased from Sigma/Aldrich (St Louis, MO)

The active forms of GLP-1 have a half-life of less than 2 min

The measured position is that the pathway is important and GHK-Cu is pleiotropic, so overlap is likely but a clean, primary demonstration that GHK-Cu drives Wnt-dependent anagen in human follicles is not something the record firmly establishes