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doi: 10.3389/fncel.2015.00003 Received 25 September 2014 Accepted 05 January 2015 Published 28 January 2015 Volume 9 - 2015 Edited by Tycho M

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Compared with placebo, the tested formulation produced a more pronounced reduction in thigh circumference and in fat mass as measured by dual-energy X-ray absorptiometry

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The same medication produces opposite bowel effects in different people, which is a strong hint that the mechanism is about motility and transit rather than about irritation

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