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In relation to obesity, genetic variants in GPX4 have been linked to obesity and inflammation in humans (38, 39), suggesting a role for GPX4 in metabolic disorders

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10.3390/ijms151119369 Int

Glucocorticoid-based combination drug therapy now dominates clinical treatments for asthma

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As insulin promotes the translocation of GLUT4 to the membrane through the activation of PI3K-AKT2-PkB pathway, there is a remodeling of the cortical actin of the cytoskeleton with subsequent contraction (Welsh et al., 2010)