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A larger phase 2b trial by Metabolic Pharmaceuticals (the original sponsor) in 2007 with 534 obese patients failed to show statistical superiority over placebo at 24 weeks

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10.3390/nu15081848 210 YangS.ZhangY.XuJ.ChenZ.RenY.LongY.et al (2025)

Acute reduction of serum 8-iso-PGF2-alpha and advanced oxidation protein products in vivo by a polyphenol-rich beverage