Ueda S, Miura K, Kawasaki H, Ogata S, Yamasaki N, Miura S
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The most common side effects of tirzepatide are gastrointestinal: Nausea: Reported by 12-33% of participants depending on dose (most common early in treatment) Diarrhea: 12-21% of participants Constipation: 6-11% of participants Vomiting: 5-13% of participants Decreased appetite: Expected therapeutic effect but can be uncomfortable These side effects are typically most intense during the first few weeks at each new dose level and tend to improve as the body adjusts
In addition, GLP-1 users and non-users agree its OK to occasionally treat yourself to a baked snack or dessert, with around 90% of those polled in each group believing baked treats/snacks can be a great reward or escape
Short-term GLP-1 use usually refers to taking the medication for 812 weeks, or up to 36 months, rather than as ongoing treatment
Researchers are still studying exactly how this effect works