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Retatrutide is a triple agonist targeting GLP-1, GIP, and glucagon receptors

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[2] [3] The relationship between GLP-1 receptor agonists and acid reflux or gastroesophageal reflux disease (GERD) symptoms is complex

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Contact your provider, monitor for severe nausea and vomiting, stay hydrated, and do not take additional doses until your next scheduled injection date

Since then, several GLP-1s for obesity have been approved for new indications such as secondary cardiovascular risk reduction (Wegovy), sleep apnea (Zepbound) and metabolic dysfunction-associated steatohepatitis or MASH (Wegovy)