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1989, 256: C1262-1266

References Hayes JD, Flanagan JU, Jowsey IR

To investigate the dose-effect relationship of OA-NPs@OA, we set up three doses: low (NPL), medium (NPM), and high (NPH) doses

As previously described 1 , the combination of drugs targeting distinct, non-overlapping pathways has proven effective in enhancing treatment efficacy

For example, certain probiotics (e.g., lactobacilli ) reportedly activate the NRF2 pathway via metabolic routes [148], while some pathogens (e.g., Salmonella , Helicobacter pylori ) activate NOX1, upregulate ROS, and induce inflammation [149]

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