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If lactose is not properly absorbed in the small intestine, it ferments in the colon

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Mutag., 3 : 395-405

This is especially true with long-term or repeated use of pain medications, where short-term relief can mask progressive systemic side effects

However, it is important to acknowledge the challenges in establishing a direct causal relationship between nutritional counseling and weight change, given the influence of confounding factors such as chemotherapy regimens in patients with AL amyloidosis

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