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Anatomically distinct fibroblast subsets determine skin autoimmune patterns

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The HR-negative hrcC mutant is still capable to elicit the unspecific, symptomless basal resistance response

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To assess the efficacy of combination treatment, tumour-bearing mice were treated as above with 5FU + metformin and CC3-quantified, showing an increase in average cell death per tumour per mouse with combination treatment (Extended Data Fig