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In sharp contrast to acute exposure, long-term exposure to high concentrations can induce compensatory hypertrophy and structural remodeling, accelerating the progression of HF
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However, active surveillance can be an optimal management modality in many patients with asymptomatic small LN metastases because repeat operations are commonly not curative and can be associated with high surgical complications, such as adjacent nerve injury and permanent hypoparathyroidism [1]
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