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These observations allowed postulating that intracellular redox state of the thiol pool, which strongly depends on GSH level, can drive autophagic response at multiple levels (Filomeni et al., 2010)

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Lima AM, de Bruin VM, Rios ER, de Bruin PF (2014) Differential effects of paradoxical sleep deprivation on memory and oxidative stress

Additionally, the reduction in -amyloid (140) levels in animals supplemented with PXN HIGH and CAF HIGH suggests a potential mechanism for the cognitive benefits observed