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Moreover, Ala-8 was substituted with an artificial amino acid, 2-amino-isobutyric acid (Aib), preventing decomposition by DPP-4

A similar shift of 6 mV has also been reported for GRX1-roGFP1-iE (Birk et al., E of roGFP probes might be a mechanical strain that acts on the GFP barrel slightly affecting the thermodynamic stability of the disulfide

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Key legal questions remain unresolved, including whether federal law overrides state claims and whether plaintiffs need specific testing to prove injury