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Stasi MA., et al

doi: 10.1016/j.jns.2017.06.042 160

Glutathione is a naturally occurring antioxidant produced by the body and found in almost every cell

However, components of the PDHc have been shown to translocate to the nucleus where they contribute to the generation of nuclear acetyl-CoA from pyruvate

That is the signature of cumulative collagen response: no single dramatic event, just gradual improvement that compounds over time

Clinical trials such as SURMOUNT-1 demonstrated significant weight reductions, averaging 1521% over 72 weeks in individuals with overweight or obesity