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The overall mitochondrial ROS burden thus surpasses the neutralizing capacity of the increased SOD2, rendering these tissues more susceptible to oxidative stress

The nucleotide was eluted with a mixture of methanol/water (1:1) into a round-bottom flask preloaded with tetrabutylammonium hydroxide (TBAH, C 16 H 37 NO, 259.48 g/mol, c = 1 M in CH 3 OH, 1 mL, 260 mg, 1 mmol, 2 equiv.)

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32 , e2240 (2022)

Pei X, Ling Y, Zhu K, Chen W, Gu M

doi: 10.1038/s41557-019-0261-6