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Availability of data and materials All data generated or analyzed during this study are included in this published article
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In the alpha cells of the islets, GLP-1 receptor activation suppresses glucagon secretion, a process mediated by somatostatin release from adjacent delta cells.54,57 Beyond the pancreas, GLP-1 receptors are widely expressed in extrapancreatic tissues, including the heart, vascular smooth muscle, lungs, liver, gastrointestinal tract, vagus nerve, and enteric nervous system.58 GLP-1 receptor agonists exhibit varying degrees of homology with endogenous GLP-1 but possess extended durations of action
On the other hand, some patients may prefer intramuscular injection therapy in order to assure effective treatment
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