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it works upstream, on an enzyme called nicotinamide N-methyltransferase (NNMT) that fat cells over-express when they become metabolically sluggish

However, brown adipose tissue mass decreased significantly in WT mice treated with AOD9604 by 20% and hGH by 31%

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Cox, Daniel Eichner Published: Drug Testing and Analysis, Volume 7, Issue 1, January 2015, pages 3138 DOI: 10.1002/dta.1715 URL: AOD9604 was incubated in human serum and rat plasma at room temperature to study in vitro metabolic degradation

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