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[DOI] [PMC free article] [PubMed] [Google Scholar] 163.Lee E., Padgett B

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Glutathione is an important antioxidant that is naturally found in every cell in the body, providing protection from free radicals and peroxides

Drug displaced from plasma protein will of course distribute throughout the volume of distribution, so that a 5% increase in the amount of unbound drug in the body produces at most a 5% increase in pharmacologically active unbound drug at the site of action

This generates GSSG, often called oxidized GSH, which is reduced by GSH reductase

Mistake 4: Ignoring dose-response curves