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That is a meaningful difference, especially at lower doses where the gap between effective and subtherapeutic is narrow
The loading period is real
Refrigerate immediately: Place the medication in your refrigerator (36-46F / 2-8C)
Res 4 , 541551 (2016)
[ref] The microbes in your gut interact with the intestinal mucosal barrier, which in turn interacts with your immune system
