Differing effects of supplemental KCl and KHCO3: pathophysiological and clinical implications
Serotypes such as AAV1, AAV6, AAV8, and especially AAV9 have demonstrated efficient cardiac transduction in small and large animals, enabling robust gene transfer to myocardium with intracoronary or intravenous delivery (Mazurek et al., 2024)
(Science-Based Medicine) Potential thyroid, kidney or metabolic disturbances some anecdotal reports and reviews raise these as possible but under-studied risks
In particular astrocytes can be a central element in maintaining mitochondrial function of dopaminergic neurones thorough transmitophagy, the process when astrocytes receive and degrade damaged neuronal mitochondria, 649 or even supply healthy mitochondria
These assumptions allow for the calculation of the intermediate respiratory state or state apparent (Supplementary Fig
SIRT-1 , Sirtuin-1