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Moreover, a significant rise in fasting levels of adiponectin by 1226% and IGF binding proteins IGFBP-1 and IGFBP-2, markers of insulin sensitivity, were reported following treatment with all doses of tirzepatide [74]
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How It Works Prebiotic fibers and short-chain fatty acid signaling Prebiotic fibers like inulin and XOS are fermented by gut bacteria into short-chain fatty acids (SCFAs), such as butyrate
3.7.1 ( 2.5.3 Construction of the protein-protein interaction (PPI) network Complex interactions among potential targets were analyzed with the STRING database ( The species was set as Homo sapiens , and the PPI network was visualized with Cytoscape v