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NRF1 (NFE2L1), a proteasome activity sensor localized to the endoplasmic reticulum, is normally degraded by ERAD

Computational identification of natural senotherapeutic compounds that mimic dasatinib based on gene expression data

Credit: Holst 2024, figure 1.2.4

30 Impaired mitophagy contributes to cardiac dysfunction and fibrosis in obesity, primary cardiomyopathies, and HIV-associated cardiomyopathy (HIVAC)

Evidence & Sources This page is reviewed by the BHRC Medical Team and updated regularly

FMT is the most comprehensive intervention that directly reprograms the gut ecosystem and has shown promising preliminary results in both experimental models and early clinical investigations