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Sasaki-Hamada showed that disruption of synaptic plasticity occurs in the prediabetes stage, when glucose tolerance is impaired

Research mapping IGF-1 receptor binding describes IGF-1R activation after IGF-I and IGF-II binding, with signalling relevance in cell growth, survival and migration models

Weight loss injections, particularly GLP-1 receptor agonists like semaglutide (Wegovy, Ozempic) and tirzepatide (Zepbound, Mounjaro), have transformed obesity treatment in the United States

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