Over 130,000 studies (and counting) have been published on the PubMed database exploring these very topics (2)
Currently NAC has the most evidence of having a beneficial effect as an adjuvant agent in the negative symptoms of schizophrenia, severe autism, depression, and obsessive compulsive and related disorders
Targeting SOD1 reduces experimental non-small-cell lung cancer
For topicals, check the glutathione concentration (e.g., 2% ) and overall formula stability
Structure of mitochondrial pyruvate carrier and its inhibition mechanism
Vitamin B12 may reduce the effectiveness of some chemotherapy drugs, such as methotrexate or 5-fluorouracil, and may also be impacted by medications like metformin, proton pump inhibitors (PPIs), and certain antibiotics (e.g., chloramphenicol)