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Izabella Wentz, Pharm.D., FASCP is a passionate, innovative and solution focused clinical pharmacist and NY Times Best Selling Author
J Investig Dermatol
Taken together, evidence from neuroscience, human research, and clinical practice suggests meaningful overlap between obesity and addiction-related mechanisms. Leggio says that his lab has long been interested in how gut-brain neuroendocrine pathways may influence alcohol use disorder (AUD)
Kynurenine is predominantly metabolized to the N -methyl-d-aspartate (NMDA) receptor agonist quinolinic acid (QUIN) in the inflammatory state, contributing to the accumulation of glutamate in the extracellular space, leading to changes in network connectivity associated with depression, fatigue and cognitive impairment
Fauser BC, Barbieri RL, Martin KA
However, this circuit can become clogged, slowed down, or dysregulated, due to the sheer volume of toxins it has to deal with
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