Food and Drug Administration (FDA) approval for the treatment of type 2 diabetes (Mounjaro ) and for chronic weight management (Zepbound )
It is administered through weekly injections, making it a convenient option for patients
These invasive gut surgical procedures, aimed to reduce absorptive surface area of the proximal GI tract, such as Roux-en-Y gastric by-pass (RYGB) or Sleeve Gastrectomy (SLG), are associated with an improved glycaemic control, weight loss, and often with complete remission from T2DM ( Despite this, the complete remittance of a great fraction of RYGB patients represents a fascinating new case-series that points at the importance of the EECs and its modulation of the whole-body metabolism ( A panoply of contradictory studies have attempted to establish what is the possible role of GLP-1 or other gut peptides in the rapid, and long-lasting remittance from T2D after bariatric surgery, but no consensus about the identity of the molecular players has yet been reached (39)
In 2026, the number of people with no commercial insurance coverage for Wegovy increased by 42 percent compared to 2025
While GLP-1 medications are powerful tools, they are not a magic fix for thyroid dysfunction itself
Because of rare thyroid tumours seen in animal studies, these drugs are avoided in people with a history of medullary thyroid carcinoma or MEN2