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The GHR-R antagonist JMV 2959 neither induces malaise nor alters the malaise property of LiCl in the adult male rat

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Bhattacharya, R

The reduction of glutathione peroxidase 4 (GPX4), an enzyme that lowers lipid hydroperoxides and inhibits lipid peroxidation, is one important mechanism (67)

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it also reflects broader issues in gut integrity and digestive resilience, which often need to be addressed in tandem