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Wu C, Luan H, Zhang X, et al

McCoy and colleagues reported that 5-day treatment of dissociated rat hippocampal neurons with Dihexa increased dendritic spine density approximately three-fold compared to vehicle control (~41 spines per 50 m of dendrite versus ~15 spines), with the increase reflecting both new spine formation and increased spine-head width consistent with synaptic maturation [2]

Murer SB, Knpfli BH, Aeberli I, et al

Melt curve analysis was conducted to verify amplification specificity

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So your heart needs to be able to respond to changing needs by beating faster or more slowly